Inicio | CIBNOR | CONACYT
    • español
    • English
  • English 
    • español
    • English
  • Login
View Item 
  •   DSpace Home
  • Recursos Digitales
  • Artículos
  • View Item
  •   DSpace Home
  • Recursos Digitales
  • Artículos
  • View Item
JavaScript is disabled for your browser. Some features of this site may not work without it.
FacebookTwitterYoutube

Browse

All of DSpaceCommunities & CollectionsBy Issue DateAuthorsTitlesSubjectsThis CollectionBy Issue DateAuthorsTitlesSubjects

My Account

LoginRegister

Prospects on the Use of Schizochytrium sp. to Develop Oral Vaccines

Thumbnail
View/Open
Prospects on the Use of Schizochytrium sp. to Develop Oral Vaccines (739.8Kb)
Author
Abel Antonio Ramos Vega
SERGIO ROSALES MENDOZA
BERNARDO BAÑUELOS HERNANDEZ
Carlos Eliud Angulo Valadez
Metadata
Show full item record
Abstract
"Although oral subunit vaccines are highly relevant in the fight against widespread diseases, their high cost, safety and proper immunogenicity are attributes that have yet to be addressed in many cases and thus these limitations should be considered in the development of new oral vaccines. Prominent examples of new platforms proposed to address these limitations are plant cells and microalgae. Schizochytrium sp. constitutes an attractive expression host for vaccine production because of its high biosynthetic capacity, fast growth in low cost culture media, and the availability of processes for industrial scale production. In addition, whole Schizochytrium sp. cells may serve as delivery vectors; especially for oral vaccines since Schizochytrium sp. is safe for oral consumption, produces immunomodulatory compounds, and may provide bioencapsulation to the antigen, thus increasing its bioavailability. Remarkably, Schizochytrium sp. was recently used for the production of a highly immunoprotective influenza vaccine. Moreover, an efficient method for transient expression of antigens based on viral vectors and Schizochytrium sp. as host has been recently developed. In this review, the potential of Schizochytrium sp. in vaccinology is placed in perspective, with emphasis on its use as an attractive oral vaccination vehicle."
URI Nacional
http://cibnor.repositorioinstitucional.mx/jspui/handle/1001/1568
URI
http://dspace.cibnor.mx:8080/handle/123456789/2925
Collections
  • Artículos

Related items

Showing items related by title, author, creator and subject.

  • Thumbnail

    PROMOCIÓN DEL PERIFITON PARA EL CULTIVO DE CAMARÓN BLANCO: HACIA UNA ACUICULTURA ECOLÓGICA 

    DOMENICO VOLTOLINA LOBINA; JUAN MANUEL AUDELO NARANJO; MARIA DEL ROSARIO PACHECO MARGES
  • Thumbnail

    Identificación y cuantificación de ciguatoxinas en peces carnívoros de la península de Yucatán 

    TAI COH LEY MARTINEZ
  • Thumbnail

    Suelo y Erosión 

    YOLANDA LOURDES MAYA DELGADO

Contact Us | Send Feedback

Centro de Investigaciones Biológicas del Noroeste, s.c.
Instituto Politécnico Nacional 195, Playa Palo de Santa Rita Sur La Paz, B.C.S. México
C.P. 23096, Tel:(52) (612) 123-8484 Fax:(52) (612) 125-3625