Inicio | CIBNOR | SECIHTI
    • español
    • English
  • English 
    • español
    • English
  • Login
View Item 
  •   DSpace Home
  • Recursos Digitales
  • Artículos
  • View Item
  •   DSpace Home
  • Recursos Digitales
  • Artículos
  • View Item
JavaScript is disabled for your browser. Some features of this site may not work without it.
FacebookTwitterYoutube

Browse

All of DSpaceCommunities & CollectionsBy Issue DateAuthorsTitlesSubjectsThis CollectionBy Issue DateAuthorsTitlesSubjects

My Account

LoginRegister

Oxidative Stress in Patients with Rheumatoid Arthritis

Thumbnail
Author
ADOLFO GARCIA GONZALEZ
RAMON GAXIOLA ROBLES
TANIA ZENTENO SAVIN
Metadata
Show full item record
Abstract
"Rheumatoid arthritis is an autoimmune disease of unknown etiology, characterized by articular inflammation. Oxidative damage induced by reactive oxygen species has been related to the pathophysiology of rheumatoid arthritis in several studies, although results have been inconsistent and contradictory. Objective: To determine oxidative stress markers in patients with rheumatoid arthritis. Methods: Descriptive cross-sectional study in rheumatoid arthritis patients and healthy controls. In peripheral blood samples from all study subjects, lipid peroxide (thiobarbituric acid reactive substances) and protein carbonyl levels were quantified as oxidative damage markers; superoxide dismutase and glutathione peroxidase activities, glutathione concentration, and the reduced glutathione/oxidized glutathione ratio were analyzed as antioxidant defense indicators. Mann- Whitney U tests were run. Statistical significance (a) was 0.05%. Results: We included 29 rheumatoid arthritis patients, 10 with active disease, and 41 healthy controls. Age was higher in the rheumatoid arthritis group; there were no differences in female:male ratio between groups. Oxidative damage was higher in rheumatoid arthritis patients; however, there was no difference between patients with active or inactive rheumatoid arthritis. Antioxidant enzyme activities, glutathione concentration, and reduced glutathione/oxidized glutathione ratio were higher in rheumatoid arthritis patients than in controls."
URI Nacional
http://cibnor.repositorioinstitucional.mx/jspui/handle/1001/759
URI
http://dspace.cibnor.mx:8080/handle/123456789/1484
Collections
  • Artículos

Related items

Showing items related by title, author, creator and subject.

  • Thumbnail

    PROMOCIÓN DEL PERIFITON PARA EL CULTIVO DE CAMARÓN BLANCO: HACIA UNA ACUICULTURA ECOLÓGICA 

    DOMENICO VOLTOLINA LOBINA; JUAN MANUEL AUDELO NARANJO; MARIA DEL ROSARIO PACHECO MARGES
  • Thumbnail

    Identificación y cuantificación de ciguatoxinas en peces carnívoros de la península de Yucatán 

    TAI COH LEY MARTINEZ
  • Thumbnail

    Suelo y Erosión 

    YOLANDA LOURDES MAYA DELGADO

Contact Us | Send Feedback

Centro de Investigaciones Biológicas del Noroeste, s.c.
Instituto Politécnico Nacional 195, Playa Palo de Santa Rita Sur La Paz, B.C.S. México
C.P. 23096, Tel:(52) (612) 123-8484 Fax:(52) (612) 125-3625